Korean J Dermatol.
2004 Apr;42(4):523-526.
A Case of Anticonvulsant Hypersensitivity Syndrome Induced by Carbamazepine
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- 1Department of Dermatology, Keimyung University School of Medicine Taegu, Korea. sfpsy@dreamwiz.com
Abstract
- Anticonvulsant hypersensitivity syndrome is a life threatening immunologic reaction of anticonvulsants therapy such as phenytoin, phenobarbital, or carbamazepine, characterized by multiple abnormalities such as fever, rash, lymphadenopathy, acute hepatocellular injury, leukocytosis, and eosinophilia. We report a case of anticonvulsant hypersensitivity syndrome thought to be caused by the use of carbamazepine in a 65-year-old male. He developed erythematous skin eruption four weeks after beginning therapy with carbamazepine. The clinical, laboratory and histologic findings of this patient were compatible with anticonvulsant hypersensitivity syndrome.
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