Korean J Dermatol.  2003 Jul;41(7):968-970.

A Case of Trichoblastoma

Affiliations
  • 1Department of Dermatology, Seoul Veterans Hospital, Korea. iam2or0@hanmail.net
  • 2Department of Pathology, College of Medicine, Chung-Ang University, Seoul, Korea.

Abstract

Trichoblastoma is a benign cutaneous neoplasm that consists of follicular germinative cells. We report a case of trichoblastoma in a 58-year-old man. The tumor was presented as a solitary symmetrical shaped pedunculated 5.0x4.0x2.0cm sized multilobular tumor on right lower leg for 2 years. Histopathologic examination showed well circumscribed dermal tumor composed of multilobular tumor islands of palisaded basaloid epithelial cells. The tumoral lobules were concentrically surrounded by hyalinized collagen bundles with fibroblasts. The overall architecture was reminiscent of hair bulbs. Cytokeratin 14 stain showed positive reaction, but cytokeratin 10 stain showed negative reaction. The tumor was completely excised with clear margin. No sign of recurrence has been noted until 9 months later.

Keyword

Trichoblastoma; Follicular germinative cell

MeSH Terms

Collagen
Epithelial Cells
Fibroblasts
Hair
Humans
Hyalin
Islands
Keratin-14
Keratins
Leg
Middle Aged
Recurrence
Collagen
Keratin-14
Keratins
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