Korean J Dermatol.
2002 Oct;40(10):1286-1288.
A Case of Cryoglobulinemia on Unusual Sites
- Affiliations
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- 1Department of dermatology, College of medicine, Dong-A university, Busan, Korea. mucca@hanmail.net
Abstract
- Cryoglobulinemia refers to the presence in the serum of one or more immunoglobulins that precipitate at temperatures below 37degrees C and that redissolve on rewarming. Type I cryoglobulin contains an isolated monoclonal immunoglobulin. The symptoms of type I cryoglobulinemia included purpura, Raynaud's phenomenon, distal ulcerations and gangrenous change caused by vascular occlusion resulting from protein precipitation. We report a case of type I cryoglobulinemia in a 72-year-old woman who had purpuras and gangrenes on her right elbow and left knee without distal skin lesions.
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