Korean J Dermatol.  2001 Aug;39(8):942-945.

Treatment of Keratoacanthoma by 5-Fluorouracil Intralesional Injection

• Kim SJ
• Jang HS
• Oh CK
• Kwon KS

Abstract

Keratoacanthoma is a not uncommon skin tumor characterized by rapid growth of a smooth dome-shaped nodule with a central plug of keratin, usually followed by spontaneous involution. Because the tumor leaves a nunsightly scar, this is one of the reasons why these lesions should be treated. Excision is desirable if the diagnosis is in doubt. But surgical removal may be difficult, alternative treatment approaches should be considered. We report two cases of keratocathoma successfully treated by intralesional injection of 5-fluorouracil.

Keyword

Keratoacanthoma; 5-Fluorouracil

MeSH Terms

Cicatrix
Diagnosis
Fluorouracil*
Injections, Intralesional*
Keratoacanthoma*
Skin
Fluorouracil