Korean J Dermatol.  2001 Jul;39(7):816-819.

A Case of Gianotti-Crosti Syndrome Associated with Epstein-Barr Virus Infection

• Jeong CW
• Park SJ
• Lee ES

Abstract

Gianotti-Crosti syndrome(GCS) is a distinct exanthematic, acrolocated eruption of childhood caused by a variety of infectious agents. Historically hepatitis B antigen positive(HBsAG+) papular acrodermatitis of childhood and HBsAg negative(HBsAg-) papulovesicular acrolocated syndrome have been distinguished. Here we present a 22-month-old female patient who developed eruptions typical for GCS and showed serologic evidence of an acute Epstein-Barr virus(EBV) infection. Serologic investigations revealed no evidence of recent infection with most common viruses except EBV infection. This case suggests that EBV infection should be sought in cases of GCS which cannot be related to HBV infection.

Keyword

Epstein-Barr virus; Gianotti-Crosti syndrome

MeSH Terms

Acrodermatitis*
Epstein-Barr Virus Infections
Female
Hepatitis B
Hepatitis B Surface Antigens
Herpesvirus 4, Human*
Humans
Infant
Hepatitis B Surface Antigens