Korean J Dermatol.  1977 Mar;15(1):69-74.

Ichthyosis Hystrix Treated by Vitamin A acid Ointment Application

• Choi YC
• Park YK

Abstract

Ichthyosis hystrix is a localized variant of Bullous Congenital Ichthyosiform Erythroderma by Broq, and also, localized form of Epidermolytic hyperkeratosis according to Frost and Van Scott's classification of ichthyosi-form dermatoses. Clinically it is generally considered to be widespread systematized epidermal nevus, and demonstrating an autosomal dominant pattem of inheritance, and characterized by verrucous scale at or shortly after birth with particular involve- ment of flexural areas. A case of 21 year old girl with ichthyosis hystrix was reported, The skin lesion showed multiple rice to pea sized linear verrucous papules on left forearm, neck, axilla and upper chest. The skin biopsy was done, the finding shows remarked laminated hyperkeratosis, acanthosis, papillomatosis, and vacuoliization on malpighian layer. Diagnosis was confirmed by clinicaI apperance and histopathologicaI finding. The method of treatment is 0. 05% Vitamin A acid ointment application and show marked improvement.

MeSH Terms

Axilla
Biopsy
Classification
Diagnosis
Female
Forearm
Humans
Hyperkeratosis, Epidermolytic
Ichthyosis*
Neck
Nevus
Papilloma
Parturition
Peas
Porcupines*
Skin
Skin Diseases
Thorax
Tretinoin*
Vitamin A*
Vitamins*
Wills
Young Adult
Tretinoin
Vitamin A
Vitamins