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Effects of different culture systems on the culture of prepuberal buffalo (Bubalus bubalis) spermatogonial stem cell-like cells in vitro

Li TT, Geng SS, Xu HY, Luo AL, Zhao PW, Yang H, Liang XW, Lu YQ, Yang XG, Lu KH

Currently, the systems for culturing buffalo spermatogonial stem cells (SSCs) in vitro are varied, and their effects are still inconclusive. In this study, we compared the effects of culture systems...
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A newborn girl with harlequin ichthyosis genetically confirmed by ABCA12 analysis

Kim J, Ko JM, Shin SH, Kim EK, Kim HS

Harlequin ichthyosis (HI, OMIM #242500) is one of the most severe skin diseases among the autosomal recessive congenital ichthyoses, with high morbidity and mortality, particularly in newborns. Clinically, it is...
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Comparative Evaluation of Hormones and Hormone-Like Molecule in Lineage Specification of Human Induced Pluripotent Stem Cells

Choi SA, An JH, Lee SH, Lee GH, Yang HJ, Jeong PS, Cha JJ, Lee S, Park YH, Song BS, Sim BW, Kim YH, Kim JS, Jin YB, Huh JW, Lee SR, Lee JH, Kim SU

BACKGROUND AND OBJECTIVES: Proficient differentiation of human pluripotent stem cells (hPSCs) into specific lineages is required for applications in regenerative medicine. A growing amount of evidences had implicated hormones and...
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Two Distinct Subsets Are Identified from the Peritoneal Myeloid Mononuclear Cells Expressing both CD11c and CD115

Sohn M, Na HY, Ryu SH, Choi W, In H, Shin HS, Park JS, Shim D, Shin SJ, Park CG

To this date, the criteria to distinguish peritoneal macrophages and dendritic cells (DCs) are not clear. Here we delineate the subsets of myeloid mononuclear cells in the mouse peritoneal cavity....
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Protective Effect of All-Trans Retinoic Acid in Cisplatin-Induced Testicular Damage in Rats

Yucel C, Arslan FD, Ekmekci S, Ulker V, Kisa E, Erdogan Yucel E, Ucar M, Ilbey YO, Celik O, Basok BI, Kozacioglu Z

PURPOSE: To investigate the effects of all-trans retinoic acid (ATRA) in cisplatin (CP)-induced testicular damage in rats. MATERIALS AND METHODS: Twenty-eight male Wistar rats were divided into four groups: Control, ATRA...
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Isolation and culture of porcine primary fetal progenitors and neurons from the developing dorsal telencephalon

Aubid NN, Liu Y, Vidal JM, Hall VJ

The development of long-term surviving fetal cell cultures from primary cell tissue from the developing brain is important for facilitating studies investigating neural development and for modelling neural disorders and...
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The Effects of Retinoic Acid and MAPK Inhibitors on Phosphorylation of Smad2/3 Induced by Transforming Growth Factor β1

Lee SH, Shin JH, Shin MH, Kim YS, Chung KS, Song JH, Kim SY, Kim EY, Jung JY, Kang YA, Chang J, Park MS

BACKGROUND: Transforming growth factor β (TGF-β), retinoic acid (RA), p38 mitogen-activated protein kinase (MAPK), and MEK signaling play critical roles in cell differentiation, proliferation, and apoptosis. We investigated the effect...
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Promyelocytic Leukemoid Reaction: Unusual Findings in a Patient with Sepsis

Kim YK

Neutrophilic leukemoid reaction may occur in many situations, including hemolysis, malignancy, infection, and exposure to certain toxins. It usually shows morphological overlap with chronic myeloid leukemia in which promyelocytes are...
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In vitro differentiation of spermatogonial stem cells using testicular cells from Guangxi Bama mini-pig

Zhao H, Nie J, Zhu X, Lu Y, Liang X, Xu H, Yang X, Zhang Y, Lu K, Lu S

In this study, we attempted to establish a culture system for in vitro spermatogenesis from spermatogonial stem cells (SSCs) of Bama mini-pig. Dissociated testicular cells from 1-month-old pigs were co-cultured...
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IL-1 Receptor Antagonist Reduced Chemical-Induced Keratinocyte Apoptosis through Antagonism to IL-1α/IL-1β

Lee H, Cheong KA, Kim JY, Kim NH, Noh M, Lee AY

Extracellular interleukin 1 alpha (IL-1α) released from keratinocytes is one of the endpoints for in vitro assessments of skin irritancy. Although cells dying via primary skin irritation undergo apoptosis as...
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Long-term control of refractory follicular lymphoma after treatment of secondary acute promyelocytic leukemia with arsenic trioxide (As₂O₃) and all-trans retinoic acid (ATRA)

Jain P, Konoplev S, Benjamini , Romagura J, Burger JA

No abstract available.
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Differentiation of human male germ cells from Wharton's jelly-derived mesenchymal stem cells

Dissanayake D, Patel H, Wijesinghe P

OBJECTIVE: Recapitulation of the spermatogenesis process in vitro is a tool for studying the biology of germ cells, and may lead to promising therapeutic strategies in the future. In this...
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Plasma CRABP2 as a Novel Biomarker in Patients with Non-Small Cell Lung Cancer

Kim DJ, Kim WJ, Lim M, Hong Y, Lee SJ, Hong SH, Heo J, Lee HY, Han SS

BACKGROUND: Lung cancer is the most common cause of cancer-related mortality worldwide. We previously reported the identification of a new genetic marker, cellular retinoic acid binding protein 2 (CRABP2), in...
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The Bromodomain Inhibitor JQ1 Enhances the Responses to All-trans Retinoic Acid in HL-60 and MV4-11 Leukemia Cells

Kang C, Kim CY, Kim HS, Park SP, Chung HM

All-trans retinoic acid (ATRA) is a highly effective treatment for acute promyelocytic leukemia (APL), a cytogenetically distinct subtype of acute myeloid leukemia (AML). However, ATRA-based treatment is not effective in...
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Control of Innate and Adaptive Lymphocytes by the RAR-Retinoic Acid Axis

Kim CH

Lymphocytes, such as T cells, B cells, and innate lymphoid cells (ILCs), play central roles in regulating immune responses. Retinoic acids (RAs) are vitamin A metabolites, produced and metabolized by...
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A Case of Atrophoderma Vermiculatum Showing a Good Response to Topical Tretinoin

Lee YC, Son SJ, Han TY, Lee JH

No abstract available.
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Scrotal Ulcer Probably Induced by All-trans Retinoic Acid Therapy in a Patient with Acute Promyelocytic Leukemia

Kim YJ, Lee WJ, Won CH, Chang SE, Choi JH, Lee MW

  • KMID: 2436640
  • Korean J Dermatol.
  • 2018 Jan;56(1):80-81.
No abstract available.
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Leukemic Pleural Effusion in Acute Promyelocytic Leukemia: A Case Report

Hwang N, Roh S, Ham JY, Suh JS

In patients with acute myeloid leukemia (AML), pleural effusion may be attributed to various factors, including infection, hypoalbuminemia, and renal failure. However, leukemic infiltration of the pleural fluid is rarely...
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Increased Skin Irritation by Hydroquinone and Rsetinoic Acid Used in Combination

Kim GH, Cheong KA, Lee AY

BACKGROUND: Hydroquinone (HQ) is frequently combined with retinoic acid (RA) to enhance lightening efficacy, which may also affect skin irritancy. Although skin irritation leads to postinflammatory hyperpigmentation, little research has...
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Eruptive Vellus Hair Cysts Successfully Treated by Topical Tretinoin 0.01% Cream

Jun JY, Oh SJ, Oh SH, Shim JH, Park JH, Lee JH, Lee DY, Lee JH, Yang JM

  • KMID: 2396230
  • Korean J Dermatol.
  • 2017 Sep;55(8):551-553.
No abstract available.
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