Korean J Fertil Steril.  2000 Sep;27(3):307-311.

A Case of Recurrent Spontaneous Abortion Successfully Delivered by Using Preimplantation Genetic Diagnosis

Abstract


OBJECTIVE
To report the successful delivery in a patient of recurrent spontaneous abortion caused by chromosomal abnormality. MATERIAL AND METHOD: Case report.
RESULTS
Twelve oocytes were obtained by in vitro fertilization. Of eleven oocytes fertilized, two embryos turned out to be normal by using fluorescent in situ hybridization on blastomere biopsy. The patient succeeded in pregnancy and the result of amniocentesis was found to be normal. She delivered the healthy female baby by cesarean section.
CONCLUSIONS
The successful delivery is possible in recurrent spontaneous abortion related with reciprocal translocation by using preimplantation genetic diagnosis.


MeSH Terms

Abortion, Spontaneous*
Amniocentesis
Biopsy
Blastomeres
Cesarean Section
Chromosome Aberrations
Embryonic Structures
Female
Fertilization in Vitro
Humans
In Situ Hybridization, Fluorescence
Oocytes
Pregnancy
Preimplantation Diagnosis*
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