Clin Pediatr Hematol Oncol.  2015 Oct;22(2):142-145. 10.15264/cpho.2015.22.2.142.

Spontaneous Remission in a Teenage Girl with Acquired Pure Red Cell Aplasia

• Kwon SE
• Kwon HW
• Kim DH
• Moon Y
• Hong YJ
• Kim SK

• KMID: 2084614
• DOI: http://doi.org/10.15264/cpho.2015.22.2.142

Abstract

Acquired pure red cell aplasia (PRCA) can be induced by various factors such as viral infection, thymoma, connective tissue disease, lymphoma, and adverse drug reactions. PRCA has not been reported in an adolescent in Korea for the past several decades. We recently experienced a case of acquired PRCA in an adolescent. A 14-year-old girl presented with pallor, dizziness, and mild fever. She had isolated normocytic normochromic anemia with reticulocytopenia in the peripheral blood and erythroblastopenia in the bone marrow. She was diagnosed with secondary acquired PRCA presumably induced by Mycoplasma pneumoniae infection during her clinical course, and she experienced spontaneous remission 11 weeks after initial diagnosis. Her clinical and hematologic statuses were normal as far as 20 months after her diagnosis.

Keyword

Acquired pure red cell aplasia; Adolescent; Mycoplasma infection; Spontaneous remission

MeSH Terms

Adolescent
Anemia
Bone Marrow
Connective Tissue Diseases
Diagnosis
Dizziness
Drug-Related Side Effects and Adverse Reactions
Female*
Fever
Humans
Korea
Lymphoma
Mycoplasma Infections
Mycoplasma pneumoniae
Pallor
Pneumonia, Mycoplasma
Red-Cell Aplasia, Pure*
Remission, Spontaneous*
Thymoma