Korean J Gastrointest Endosc.  1997 Oct;17(5):716-722.

Clinical Usefulness of Magnetic Resonance Cholangiagraphy and Computed Tomography Cholangiography in Primary Sclerosing Cholangitis

• Yang DK
• Kim SS
• Kang DH
• Park HC
• Kim ES
• Kim EA
• Ha SY
• Yang DM
• Park JJ

Abstract

Primary sclerosing cholangitis(PSC) is rare disease which is characterized by inflammation and obliteration of bile duct leading to biliary cirrhosis and liver failure. The cause of PSC is unknown although a number of potential etiologic factor have been investigated. The diagonsis is confirmed by typical cholangiographic demonstration with clinical features. On endoscopic retrograde cholangiopancreatography(ERCP), multifocal strictures involving both intra and extrahepatic bile ducts are most common; they were diffusely distributed, short, and annular, alternating with normal or slightly dilated segments to produce a "beaded" appearance, the "pruned-tree" appearance due to diminished arborization of the intrahepatic duct, band-like stricture, and diverticular-like outpouching(s) are seen occasionally on cholangiography, and the report of primary sclerosing cholangitis in Korea is being increased due to increased use of ERCP. Recently, magnetic resonance cholangiography(MR cholangiography) and computed tomography cholangiography(CT cholangiography) are newly developed adjunctives for evaluation of patients with biliary disease(s). We performed MR cholangiography and CT cholangiography through the nasobiliary tube in two patients with PSC, in which typical intrahepatic bile duct changes of PSC were seen as in ERCP. Now, we report MR cholangiographic and CT cholangiographic findings in patients with PSC and suggest that these radiologic studies, especially MR cholangiography, can be used as an alternative methods for serial follow-up after definite diagnosis by ERCP.

Keyword

Primary sclerosing cholangitis; Magnetic resonance cholangiography; ERCP

MeSH Terms

Bile Ducts
Bile Ducts, Extrahepatic
Bile Ducts, Intrahepatic
Cholangiography*
Cholangiopancreatography, Endoscopic Retrograde
Cholangitis, Sclerosing*
Constriction, Pathologic
Diagnosis
Follow-Up Studies
Humans
Inflammation
Korea
Liver Cirrhosis, Biliary
Liver Failure
Rare Diseases