Korean J Gastrointest Endosc.  1995 Sep;15(3):458-464.

Hemostatic Effect of Endoscopic Injection with Hypertonic Saline - Epinephrine (HS-E) Solution in Petic Ulcer Bleeding

• Yook EJ
• Im EH
• Jeong HY
• Lee HY
• Kim YK
• Kim SG
• Kim JH
• Seo KS
• Kim NJ

Abstract

Peptic ulcer bleeding is the most common cause of upper gastromtestinal bleeding. The efficacy of local injection of hypertonic saline-epinephrine(RS-E)solutiom around the base of the bleeding vessels under endoscopy was assessed, During the period between January 1991 and August 1994, 83 patients with active bleeding or stigmata of recent hemorrhage in peptic ulcers were included to this study. The major cause of bleeding in this study consisted of gastric ulcers(60) and duodenal ulcers(23). Twenty patients rebled and seven required emergency surgery and two patients were died. Definitive hemoatasis was achieved in 74(89.3%). Two patients rebled due to mucosal ischemia induced by HS-E injection, other significant complication was not found. We conclude that the endoscopic injection with hypertonic saline-epinephrine solution is one of the effective and safe therapeutic modality in peptic ulcer bleeding.

Keyword

Peptic ulcer bleeding; Hypertonic Saline - Epinephrine solution; Endoscopic injection

MeSH Terms

Christianity
Emergencies
Endoscopy
Epinephrine*
Hemorrhage*
Humans
Ischemia
Peptic Ulcer
Ulcer*
Epinephrine