Korean J Helicobacter Up Gastrointest Res.  2015 Mar;15(1):49-52. 10.7704/kjhugr.2015.15.1.49.

A Case of Successful Endoscopic Submucosal Dissection of Gastric Adenoma in a Patient with Congenital Factor VII Deficiency

• Kim SH
• Choi SH
• Lee JW
• Shin WJ
• Bang CS
• Baik GH

• KMID: 2083686
• DOI: http://doi.org/10.7704/kjhugr.2015.15.1.49

Abstract

Congenital factor VII deficiency is a rare hemorrhagic disorder, and invasive procedures are likely to cause excessive bleeding in these patients. Endoscopic submucosal dissection (ESD) has been accepted as a curative treatment modality for gastric adenoma, early gastric cancer (EGC) and any other mucosal and submucosal tumors. The most important complications of ESD are bleeding and perforation. The use of antiplatelet agents or coagulopathies are risk factors for these complications. There are only few reports of successful ESD with coagulation disorders. We report a case of a 70-year-old female patient who was diagnosed with a gastric adenoma and factor VII deficiency. The patient was successfully treated with ESD. Before ESD, recombinant Coagulation factor VIIa was injected, and the procedure was performed successfully without any complications. In conclusion, ESD can be performed successfully in patients with factor VII deficiency, when recombinant human factor VIIa is administered properly.

Keyword

Factor VII deficiency; Endoscopy; Stomach neoplasms

MeSH Terms

Adenoma*
Aged
Endoscopy
Factor VII Deficiency*
Factor VIIa
Female
Hemorrhage
Hemorrhagic Disorders
Humans
Platelet Aggregation Inhibitors
Risk Factors
Stomach Neoplasms
Factor VIIa
Platelet Aggregation Inhibitors