Korean J Med Mycol.  2003 Mar;8(1):16-20.

A Case of Primary Cutaneous Cryptococcosis Misdiagnosel as Skin Tuberculosis

Affiliations
  • 1Department of Dermatology, College of Medicine, Chung Ang University, Seoul, Korea. drro2@hananet.net

Abstract

Cryptococcosis is an opportunistic yeast infection caused by Cryptococcosis neoformans. The cutaneous manifestations are usually polymorphic and nonspecific. Lesions may appear as subcutaneous swelling, abscesses, tumor-like masses, papules or large ulcers. Therefore, diagnosis of cutaneous cryptococcosis is quite difficult and often delayed. Clinical suspicion is very important in diagnosis. A 47-year-old man presented with a ulcerative nodule on the right side of the neck. Because initial skin biopsy revealed granulomatous lesion, we misdiagnosed his lesion as skin tuberculosis and treated him with anti tuberculosis medication for 6 months. But his symptom was not improved. After second biopsy specimen had showed some spores with narrow neck budding, we confirmed this case as a cryptococcosis and successfully treated with itraconazole (200 mg/day) for 12 weeks.

Keyword

Primary cutaneous cryptococcosis

MeSH Terms

Abscess
Biopsy
Cryptococcosis*
Diagnosis
Humans
Itraconazole
Middle Aged
Neck
Skin*
Spores
Tuberculosis
Tuberculosis, Cutaneous*
Ulcer
Yeasts
Itraconazole
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