Korean J Nucl Med.  2003 Oct;37(5):336-339.

Osteogenic Sarcoma with Osseous, Pulmonary, and Pericardial Metastases Simultaneously Demonstrated on Bone Scintigraphy at Initial Presentation

Affiliations
  • 1Department of Nuclear Medicine, Chonbuk National University Medical School, Chonju, Korea. mhsohn@moak.chonbuk.ac.kr
  • 2Department of Pediatrics, Chonbuk National University Medical School, Chonju, Korea.
  • 3Institute for Medical Sciences, Chonbuk National University Medical School, Chonju, Korea.
  • 4Research Institute of Clinical Medicine, Chonbuk National University Medical School, Chonju, Korea.

Abstract

PURPOSE
A 6-year-old boy with osteogenic sarcoma of the left humerus underwent bone scintigraphy. Tc-99m MDP was accumulated not only in the primary tumor but also in the osseous and extraosseous (pulmonary and pericardial) metastases. Osteogenic sarcoma directly produces osteoid, both in the primary and metastatic lesions. Tc-99m MDP is avidly taken up by tumor osteoid. At initial presentation, only 2% of cases have both pulmonary and osseous metastases. The patient had osseous, pulmonary, and pericardial metastases at presentation. This case presents that increased uptakes of Tc-99m MDP by the primary and metastatic tumor were demonstrated on bone scintigraphy at presentation.

Keyword

Osteogenic sarcoma; metastases; extraosseous uptake; Tc-99m MDP; bone scintigraphy

MeSH Terms

Child
Humans
Humerus
Male
Neoplasm Metastasis*
Osteosarcoma*
Radionuclide Imaging*
Technetium Tc 99m Medronate
Technetium Tc 99m Medronate
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