Korean J Obstet Gynecol.  2012 Aug;55(8):539-545. 10.5468/KJOG.2012.55.8.539.

Perinatal outcomes of fetal growth restriction between late preterm and term birth infants

• Surh JS
• Hwang SA
• Park HN
• Jeon SJ
• Lee SP
• Nam KH
• Kim SY
• Son DW
• Shim SY
• Joe HJ

• KMID: 2078102
• DOI: http://doi.org/10.5468/KJOG.2012.55.8.539

Abstract

OBJECTIVE
To estimate the absolute increase in the risk for adverse neonatal outcomes of fetal growth restriction between late preterm and term birth and to identify risk factors for neonatal morbidity among late preterm and term birth infants.
METHODS
A retrospective review of 2,954 singleton infant between 34 and 42 weeks of gestation born at our hospital over the 5 years were enrolled and they were divided into four groups as late preterm small for gestational age (SGA), late preterm adequate for gestational age (AGA), term SGA and term AGA, respectively. The prenatal ultrasonographic findings between SGA and AGA in late preterm birth were assessed. Maternal and neonatal complications were compared with SGA and AGA between late preterm and term birth infants. The statistical analyses for frequencies and relative risks in each group were calculated by SPSS ver. 19.0.
RESULTS
In prenatal evaluation between SGA and AGA in late preterm birth, amniotic fluid volume, abdominal circumference and umbilical artery Doppler resistance index value were different significantly (P<0.001). Preeclampsia and oligohydramnios were found more common in SGA of late preterm birth compared with AGA of term birth. Jaundice, respiratory distress syndrome, necrotizing enterocolitis, sepsis, congenital anomalies, hypoglycemia, and germinal matrix's hemorrhage, occurred more frequent in SGA of late preterm birth than in AGA of term birth.
CONCLUSION
Not only adequate prenatal evaluation and obstetrical decision-making but also long-term evaluation are needed to improve perinatal outcomes of growth restricted infants in late preterm birth.

Keyword

Late preterm; Small for gestational age; Adequate for gestational age; Perinatal outcomes; Maternal outcomes

MeSH Terms

Amniotic Fluid
Enterocolitis, Necrotizing
Female
Fetal Development
Gestational Age
Hemorrhage
Humans
Hypoglycemia
Infant
Jaundice
Oligohydramnios
Pre-Eclampsia
Pregnancy
Premature Birth
Retrospective Studies
Risk Factors
Sepsis
Term Birth
Umbilical Arteries

Figure

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  Fig. 1 SGA and AGA in late preterm birth and term birth infants for 5 years. SGA, small for gestational age; AGA, adequate for gestational age; PT, (late) preterm; T, term.

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