Korean J Obstet Gynecol.  2008 Jul;51(7):766-770.

Two cases of complete chorioamniotic membrane separation

• Hong JH
• Kim YS
• Park JH
• Jeon S
• Choi SD
• Sunwoo JG
• Bae DH

Abstract

As chorion and amnion fusion usually occurs between 14 and 16 weeks of gestation, sonographic identification of chorion and amniotic membrane separation is a normal finding before 14 weeks. However, persistent separation after 16 weeks of gestation is considered rare and abnormal findings. Complete chorioamniotic membrane separation (CMS) may occur spontaneously, but has also been described as a complication of all invasive intrauterine procedures, including amniocentesis. Complete CMS have a significant morbidity and mortality due to intrauterine fetal death, cord complications, and preterm delivery. Aggressive treatment with hospitalization is necessary. We now report 2 cases of complete CMS identified by prenatal ultrasound; 1 in spontaneous complete CMS diagnosed at 24 weeks of gestation, and health premature child was born at 29+3 weeks of gestation, who was alive and well at present; 1 in complete CMS diagnosed at 21 weeks of gestation after amniocentesis, and fetal demise at 24 weeks of gestation due to cord strangulation by an amniotic band. We experienced two cases of complete CMS and report with a brief review of literatures.

Keyword

Complete chorioamniotic membrane separation; Amniocentesis; Intrauterine fetal death

MeSH Terms

Amniocentesis
Amnion
Amniotic Band Syndrome
Child
Chorion
Fetal Death
Hospitalization
Humans
Infant, Newborn
Membranes
Pregnancy