Korean J Obstet Gynecol.
2006 Sep;49(9):1993-1998.
A case of low-grade endometrial stromal sarcoma with multiple metastasis
- Affiliations
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- 1Department of Obstetrics and Gynecology, Yong Dong Severance Hospital, Korea. jaehoonkim@yumc.yonsei.ac.kr
- 2Department of Pathology, Yong Dong Severance Hospital, Korea.
- 3Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University Collage of Medicine, Seoul, Korea.
Abstract
- Uterine sarcomas are rare tumors of mesodermal origin and constitute 2-6% of uterine malignancies. They are classified into leiomyosarcoma (LMS), malignant mixed mullerian tumors (MMMTs), and endometrial stromal sarcoma (ESS) by histologic types. Endometrial stromal sarcomas account for about 7-15% of uterine sarcomas, about 0.2% of female genital tract malignancies. Endometrial stromal sarcomas are divided into endometrial stromal nodule, low-grade endometrial stromal sarcoma, and high-grade endometrial stromal sarcoma on the basis of mitotic activity and vascular invasion. Clinical outcome of low-grade endometrial sarcoma is better than that of high-grade endometrial stromal sarcoma and has a propensity for slow metastasis. We have experienced a case of low-grade endometrial stromal sarcoma with multiple metastasis in a 41-year-old woman and was treated by surgical resection and combination chemotherapy, which is presented with a review of brief literature.
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