Korean J Obstet Gynecol.  2006 Sep;49(9):1902-1907.

Clinical analysis of synchronous primary neoplasms of the female reproductive tract

• Tong SY
• Lee YS
• Park JS
• Lee JM
• Namkoong S

Abstract

OBJECTIVE
A histopathologic review of synchronous primary neoplasms of the female reproductive tract was presented and the possible correlation among discrete tumor subsets, natural history, and survival was evaluated.
METHODS
Between 2000 and 2005, 20 patients with synchronous primary cancers of the gynecologic malignancy were identified. Clinical and pathologic informations were obtained from medical records. Kaplan-Meier survival analysis was performed.
RESULTS
The patients with Synchronous primary malignancies constituted 0.63% of all genital malignancies. The most frequently observed synchronous neoplasms were those of the ovary with the endometrium (40%). The mean age of patient with synchronous ovarian and endometrial cancer was 45.2 years. 8 patients underwent the hysterectomy with bilateral salpingo-oophorectomy and adjuvant therapy. The mean survival is 57 months (SE 10.0, 95% Confidence interval 37-77).
CONCLUSION
Synchronous ovarian and endometrial cancers were detected in relatively early age and the prognosis was favorable.

Keyword

Synchronous neoplasm; Endometrial cancer; Ovarian cancer; Prognosis

MeSH Terms

Endometrial Neoplasms
Endometrium
Female*
Humans
Hysterectomy
Medical Records
Natural History
Neoplasms, Multiple Primary
Ovarian Neoplasms
Ovary
Prognosis