Korean J Obstet Gynecol.  2004 Jul;47(7):1385-1388.

Successful Pregnancy after Paclitaxel-Cisplatin Chemotherapy in Invasive Squamous Cell Carcinoma of Cervix During Pregnancy: A Case Report and Review of the Literature

• Yu SY
• Ryu SR
• Cha SH
• Han JY
• Jung JH

Abstract

Paclitaxel-Cisplatin based chemotherapy in invasive squamous cell carcinoma of cervix during pregnancy has not been reported previously. A woman was diagnosed with stage II b invasive squamous cell carcinoma of cervix during pregnancy at 27 weeks gestational age. She was treated with two cycles of paclitaxel and cisplatin during pregnancy. At 36 weeks, she underwent a classical cesarean section and bilateral paraaortic lymphadenectomy. One additional cycles of chemotherapy and radiotherapy were given. She developed a recurrence within 6 months of surgery. The infant has normal growth and development at 4.3 months of age. This is the first reported case of paclitaxel-cisplatin use in cervical cancer during pregnancy.

Keyword

Paclitaxel; Cisplatin; Pregnancy

MeSH Terms

Carcinoma, Squamous Cell*
Cervix Uteri*
Cesarean Section
Cisplatin
Drug Therapy*
Female
Gestational Age
Growth and Development
Humans
Infant
Lymph Node Excision
Paclitaxel
Pregnancy*
Radiotherapy
Recurrence
Uterine Cervical Neoplasms
Cisplatin
Paclitaxel