Soonchunhyang Med Sci.  2017 Jun;23(1):56-60. 10.0000/sms.2017.23.1.56.

Ovarian Squamous Cell Carcinoma Associated with Endometriosis: Poor Response to Chemotherapy

• Jeon S

• KMID: 2404880
• DOI: http://doi.org/10.0000/sms.2017.23.1.56

Abstract

The occurrence of ovarian squamous cell carcinoma associated with ovarian endometriosis is extremely rare. Several studies revealed poor prognosis for ovarian squamous cell carcinoma especially when associated with endometriosis. We report a case of ovarian squamous cell carcinoma that invades the parametrium that is also associated with ovarian endometriosis. A 41-year-old woman with stage IIB ovarian squamous cell carcinoma was treated with debulking surgery followed by six courses combination chemotherapy composed of paclitaxel and carboplatin. Twenty months after the last course of chemotherapy (3 months after normal positron emission tomography-computed tomography [CT] scanning), upper abdominal pain developed and abdomen CT scan revealed multiple metastasis in liver and paraaortic lymph node. Although two cycles of paclitaxel and cisplatin was administrated, she died of disease three months after the recurrence.

Keyword

Squamous cell carcinoma; Endometriosis; Chemotherapy

MeSH Terms

Abdomen
Abdominal Pain
Adult
Carboplatin
Carcinoma, Squamous Cell*
Cisplatin
Drug Therapy*
Drug Therapy, Combination
Electrons
Endometriosis*
Epithelial Cells*
Female
Humans
Liver
Lymph Nodes
Neoplasm Metastasis
Paclitaxel
Prognosis
Recurrence
Tomography, X-Ray Computed
Carboplatin
Cisplatin
Paclitaxel