Korean J Obstet Gynecol.
2001 Nov;44(11):1968-1972.
The significance of the TDx-FLM assay in the fetal lung maturity
- Affiliations
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- 1Department of Obstetrics and Gynecology, College of Medicine, Inha University.
- 2Department of Nuclear Medicine, College of Medicine, Inha University.
- 3Department of Preventive Medicine, College of Medicine, Inha University.
- 4Department of Clinical Pathology? College of Medicine, Inha University.
Abstract
OBJECTIVE
The TDX analyzer, an automated fluorescence polarimeter, has been utilized to assess surfactant content in amniotic fluid. Amniostat-FLM is an immunologic semiquantitative agglutination test for determining the presence of phosphatidylglycerol in human amniotic fluid at concentration indicative of fetal lung maturity. We evaluated the usefulness of the recently introduced TDx-FLM assay in determining fetal lung maturity.
METHODS
Seventy-three samples of amniotic fluid were analyzed. Among them, 18 samples were compared with Amniostat-FLM assay.
RESULTS
Surfactant/albumin ratio using TDx-FLM assay increased with longer gestational age. And the concordance rate between Amniostat-FLM assay and TDx-FLM assay was 66.9%.
CONCLUSION
The TDx-FLM assay appears to be a useful test in the field of fetal lung maturity testing.
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