Korean J Obstet Gynecol.
1997 Sep;40(9):2087-2091.
Two Cases of Sertoli-Leydig Cell Tumor without Masculinized Symptom
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- 1Department of Obstetrics and Gynecology, Wallace Memorial Baptist Hospital, Pusan, Korea.
Abstract
- Sertoli-Leydig cell tumor is an uncommon tumor that may manifest itself by a characteri-stic virilization symptom. It is a rare gonadal tumor of sex-cord type, representing only 0.1~0.5% of all primary ovarian neoplasm. These tumors are the most common virilizing tumors in women of reproductive age. However, only one-third of patients develop masculinization. We have seen two cases of Sertoli-Leydig cell tumors without the virilizing symptom. These two cases have been confirmed by permanent tissue biopsies and have been presented in a 32-year old female who has had only amenorrhea and in a 56-year old postmenopausal female who has not manifested virilizing symptom. These cases are presented with brief review of the literature.
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