Korean J Pathol.  2004 Oct;38(5):330-332.

Toxoplasmic Lymphadenitis with Toxoplasma Bradyzoites: A Case Report

Affiliations
  • 1Department of Pathology, Kwandong University College of Medicine, Myongji Hospital, Goyang, Korea. ohe11@hanmail.net
  • 2Department of Pathology, Korea University College of Medicine, Seoul, Korea.

Abstract

Toxoplasmic lymphadenitis is the most frequently observed clinical form of acquired toxoplasmosis. It is diagnosed by observing the characteristic histopathology, performing serologic tests and demonstrating the organisms. However, detection of the organisms in lymph node section is rarely accomplished. We demonstrate a case of a toxoplasmic lymphadenitis of a 40-year-old man with bradyzoites. The histopathologic findings of the lymph nodes showed reactive follicular hyperplasia associated with the presence of irregular clusters of epithelioid histiocytes, usually located in the cortical and paracortical zones, and monocytoid B cell proliferation. We demonstrated the bradyzoites of Toxoplasma gondii with periodic acid-Schiff (PAS)-stain, and serologic testing showed positive Ig-G and Ig-M toxoplasma antibodies.

Keyword

Toxoplasma Lymphadenitis; Bradyzoites; PAS stain

MeSH Terms

Adult
Antibodies
Cell Proliferation
Histiocytes
Humans
Hyperplasia
Lymph Nodes
Lymphadenitis*
Serologic Tests
Toxoplasma*
Toxoplasmosis
Antibodies
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