Korean J Pediatr Hematol Oncol.
1999 Apr;6(1):162-167.
A Case of Malignant Gastric Stromal Tumor
- Affiliations
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- 1Department of Pediatrics, Pochun Cha Medical University, Pundang Cha Hospital, Sungnam, Korea.
- 2Department of Internal Medicine, Pochun Cha Medical University, Pundang Cha Hospital, Sungnam, Korea.
- 3Department of General Surgery, Pochun Cha Medical University, Pundang Cha Hospital, Sungnam, Korea.
- 4Department of Clinical Pathology, Pochun Cha Medical University, Pundang Cha Hospital, Sungnam, Korea.
- 5Department of Pathology, Pochun Cha Medical University, Pundang Cha Hospital, Sungnam, Korea.
Abstract
- As leiomyosarcomas of smooth muscle origin are rare tumors found in adults, they are even more uncommon among children. Therefore, most of the existing literatures concerning pediatric leiomyosarcomas has been limited to case reports. More recently, ultrastructural and immunohistochemical studies revealed that some tumors may have properties more suggestive of nerve cells or vascular endothelial cells, rendering the gastrointestinal stromal tumor a more popular term. We experienced a 13 year old boy who was diagnosed and treated as iron deficiency anemia. Even after iron therapy, he had persistent anemia and endoscopic examination revealed a huge mass in the gastric cardia. Proximal gastrectomy was performed with margins free of tumor. The tumor cells showed high mitotic activity suggesting malignant nature. The immunohistochemical staining was positive for smooth muscle actin while negative for S-100 protein. Brief review of the literatures are presented.
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