Korean J Pediatr Hematol Oncol.  1999 Apr;6(1):151-155.

Two Cases of Glaucoma Developed during Induction Chemotherapy Including Steroid in Childhood Acute Lymphoblastic Leukemia

Affiliations
  • 1Department of Ophthalmology, Catholic University Medical College, Seoul, Korea.
  • 2Department of Pediatrics, Catholic University Medical College, Seoul, Korea.

Abstract

The purpose of the study is to minimize the incidence of glaucoma and ocular hypertension caused by using corticosteroids during induction chemotherapy for acute lymphoblastic leukemia in children. We have periodically observed the intraocular pressure and the variation of C / D ratio of two 7 years old boys with chemotherapy in our pediatric department. We observed the increase in intraocular pressure using applanation tonometer, and we managed by beta- blockers, carbonic anhydrase inhibitor and etc. Increased intraocular pressure has been normalized after chemotherapy. The frequency of occurrence of the ocular hypertension and glaucoma can be controlled with the quantity of corticosteroids used.

Keyword

Glaucoma; Leukemia; Steroid

MeSH Terms

Adrenal Cortex Hormones
Carbonic Anhydrases
Child
Drug Therapy
Glaucoma*
Humans
Incidence
Induction Chemotherapy*
Intraocular Pressure
Leukemia
Ocular Hypertension
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
Adrenal Cortex Hormones
Carbonic Anhydrases
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