J Korean Neurosurg Soc.  1992 Sep;21(9):1110-1120.

Callosotomy for Intractable Epilepsy in Children

• Choi JU
• Yoon SH
• Lee BI

Abstract

Four children with medically refractory multiform seizures were submitted for section of the corpus callosum for last 3 years. These patients had medically intractable generalized seizures diagnosed preoperatively as the Lennox-Gastaut syndrome characterized by a combination of seizure patterns, most frequently drop attack with generalized tonic-clonic, generalized tonic and atonic seizure. Guided by pre- and intra-operative electroencephalographic monitoring, the section was carried out in the anterior 2/3 or 4/5 part of callosum. Five to 28 months' postoperative follow-up suggests good results:Three patient showed no more drop attack except intermittent focal myoclonic seizures in 1 case and one patient had generalized seizures less in frequency than preoperative state. Corpus callosotomy seems to be an effective surgical approach for the intractable epilepsy with drop attack of multifocal origin, but longer follow-up is needed.

Keyword

Callosotomy; Epilepsy; Electroencephalography

MeSH Terms

Child*
Corpus Callosum
Electroencephalography
Epilepsy*
Follow-Up Studies
Humans
Seizures
Syncope