J Korean Neurosurg Soc.  2006 Feb;39(2):148-151.

Brain Metastasis from Dermatofibrosarcoma Protuberans

• Kim WH
• Park CK
• Kim DG
• Jung HW

Abstract

Dermatofibrosarcoma protuberans(DFSP) is an uncommon fibrohistiocytic tumor characterized by aggressive local invasion and consequent local recurrence rather than distant metastasis. We present a case of a 51-year-old male patient with a typical cutaneous DFSP, which showed local recurrences and distant metastasis to the central nervous system(CNS) and the lung after 15 years from the initial diagnosis. CNS metastatic lesions recurred in 5 months after surgical resection of the first CNS lesion. These metastatic tumors were treated by open surgery and gamma-knife radiosurgery. Despite continuous medication of oral chemotherapeutic agent, the patient died during 1-year follow-up period.

Keyword

Dermatofibrosarcoma protuberans; Brain metastasis

MeSH Terms

Brain*
Dermatofibrosarcoma*
Diagnosis
Follow-Up Studies
Humans
Lung
Male
Middle Aged
Neoplasm Metastasis*
Radiosurgery
Recurrence