J Gastric Cancer.  2011 Sep;11(3):135-140. 10.5230/jgc.2011.11.3.135.

Gastric Cancer Epidemiology in Korea

Affiliations
  • 1Cancer Epidemiology Branch, National Cancer Center, Goyang, Korea. shina@ncc.re.kr
  • 2Cancer Registration and Statistics Branch, National Cancer Center, Goyang, Korea.

Abstract

Gastric cancer has been the most commonly diagnosed cancer in Korea although the age-standardized mortality and incidence has decreased gradually during last two decades. Helicobacter pylori infection and cigarette smoking are well-established risk factors, and the role of dietary factors, such as salted foods, fresh vegetables and fruits, soy foods, and processed or grilled meats on gastric carcinogenesis has been suggested. In this review, we review national and international gastric cancer statistics, studies on environmental risk factors conducted in the Korean population, and gastric cancer screening activities.

Keyword

Stomach neoplasms; Epidemiology; Incidence; Mortality; Risk factors

MeSH Terms

Fruit
Helicobacter pylori
Incidence
Korea
Mass Screening
Meat
Risk Factors
Smoking
Soy Foods
Stomach Neoplasms
Vegetables

Figure

  • Fig. 1 Incidence (1999~2008) and mortality (1983~2009) of gastric cancer in Korea. Age standardization was performed using the middle year population of 2000 as a standard population (4).

  • Fig. 2 Comparison of incidence and mortality of gastric cancer in selected countries with age-standardized rates per 100,000 using the World Health Organization world standard population (1).


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Reference

1. Accessed July 29, 2011. http://globocan.iarc.fr/.
2. Shin A, Park S, Shin HR, Park EH, Park SK, Oh JK, et al. Population attributable fraction of infection-related cancers in Korea. Ann Oncol. 2011; 22:1435–1442. PMID: 20974652.
Article
3. Jung KW, Park S, Kong HJ, Won YJ, Lee JY, Park EC, et al. Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2008. Cancer Res Treat. 2011; 43:1–11. PMID: 21509157.
Article
4. Accessed July 21, 2011. http://www.kosis.kr/.
5. Jung KW, Park S, Won YJ, Kong HJ, Lee JY, Park EC, et al. Prediction of cancer incidence and mortality in Korea, 2011. Cancer Res Treat. 2011; 43:12–18. PMID: 21509158.
Article
6. World Health Organization International Agency for Research on Cancer. Schistosomes, Liver Flukes and Helicobacter pylori. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. 1994. Lyon: International Agency for Research on Cancer.
7. Bouvard V, Baan R, Straif K, Grosse Y, Secretan B, El Ghissassi F, et al. WHO International Agency for Research on Cancer Monograph Working Group. A review of human carcinogens--Part B: biological agents. Lancet Oncol. 2009; 10:321–322. PMID: 19350698.
Article
8. Helicobacter and Cancer Collaborative Group. Gastric cancer and Helicobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts. Gut. 2001; 49:347–353. PMID: 11511555.
9. Chang WK, Kim HY, Kim DJ, Lee J, Park CK, Yoo JY, et al. Association between Helicobacter pylori infection and the risk of gastric cancer in the Korean population: prospective case-controlled study. J Gastroenterol. 2001; 36:816–822. PMID: 11777209.
10. Cho SJ, Choi IJ, Kim CG, Lee JY, Kook MC, Seong MW, et al. Helicobacter pylori seropositivity is associated with gastric cancer regardless of tumor subtype in Korea. Gut Liver. 2010; 4:466–474. PMID: 21253294.
11. Kim DS, Lee MS, Kim YS, Kim DH, Bae JM, Shin MH, et al. Effect modification by vitamin C on the relation between gastric cancer and Helicobacter pylori. Eur J Epidemiol. 2005; 20:67–71. PMID: 15756906.
12. Lee SA, Kang D, Shim KN, Choe JW, Hong WS, Choi H. Effect of diet and Helicobacter pylori infection to the risk of early gastric cancer. J Epidemiol. 2003; 13:162–168. PMID: 12749604.
13. Shin A, Shin HR, Kang D, Park SK, Kim CS, Yoo KY. A nested case-control study of the association of Helicobacter pylori infection with gastric adenocarcinoma in Korea. Br J Cancer. 2005; 92:1273–1275. PMID: 15756269.
14. Gwack J, Shin A, Kim CS, Ko KP, Kim Y, Jun JK, et al. CagA-producing Helicobacter pylori and increased risk of gastric cancer: a nested case-control study in Korea. Br J Cancer. 2006; 95:639–641. PMID: 16909137.
15. Yim JY, Kim N, Choi SH, Kim YS, Cho KR, Kim SS, et al. Seroprevalence of Helicobacter pylori in South Korea. Helicobacter. 2007; 12:333–343. PMID: 17669107.
16. Secretan B, Straif K, Baan R, Grosse Y, El Ghissassi F, Bouvard V, et al. WHO International Agency for Research on Cancer Monograph Working Group. A review of human carcinogens--Part E: tobacco, areca nut, alcohol, coal smoke, and salted fish. Lancet Oncol. 2009; 10:1033–1034. PMID: 19891056.
Article
17. Kim Y, Shin A, Gwack J, Jun JK, Park SK, Kang D, et al. Cigarette smoking and gastric cancer risk in a community-based cohort study in Korea. J Prev Med Public Health. 2007; 40:467–474. PMID: 18063902.
Article
18. Yun YH, Jung KW, Bae JM, Lee JS, Shin SA, Park SM, et al. Cigarette smoking and cancer incidence risk in adult men: National Health Insurance Corporation Study. Cancer Detect Prev. 2005; 29:15–24. PMID: 15734213.
Article
19. Jee SH, Samet JM, Ohrr H, Kim JH, Kim IS. Smoking and cancer risk in Korean men and women. Cancer Causes Control. 2004; 15:341–348. PMID: 15141135.
Article
20. Parkin DM, Pisani P, Ferlay J. Estimates of the worldwide incidence of eighteen major cancers in 1985. Int J Cancer. 1993; 54:594–606. PMID: 8514451.
Article
21. Shikata K, Doi Y, Yonemoto K, Arima H, Ninomiya T, Kubo M, et al. Population-based prospective study of the combined infl uence of cigarette smoking and Helicobacter pylori infection on gastric cancer incidence: the Hisayama Study. Am J Epidemiol. 2008; 168:1409–1415. PMID: 18945691.
22. Lee H, Yoon SJ, Ahn HS. Measuring the burden of major cancers due to smoking in Korea. Cancer Sci. 2006; 97:530–534. PMID: 16734732.
Article
23. Report on National Health and Nutritional Examination, 1969-2005. 2007. Ministry of Health and Welfare.
24. WHO/FAO Expert Consultation. Diet, Nutrition and the Prevention of Chronic Diseases. 2003 WHO Technical Report Series No. 916. 2003. Geneva, Switzerland: World Health Organization.
25. World Cancer Research Fund, American Institute for Cancer Research. Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective. 2007. Washington DC: World Cancer Research Fund.
26. Park B, Shin A, Park SK, Ko KP, Ma SH, Lee EH, et al. Ecological study for refrigerator use, salt, vegetable, and fruit intakes, and gastric cancer. Cancer Causes Control. 2011; 7. 30. [Epub ahead of print].
Article
27. Kim J, Park S, Nam BH. Gastric cancer and salt preference: a population-based cohort study in Korea. Am J Clin Nutr. 2010; 91:1289–1293. PMID: 20219954.
Article
28. Nan HM, Park JW, Song YJ, Yun HY, Park JS, Hyun T, et al. Kimchi and soybean pastes are risk factors of gastric cancer. World J Gastroenterol. 2005; 11:3175–3181. PMID: 15929164.
Article
29. Lee S, Kang D, Hong WS, Shim KN, Choe JW, Choi H. Dietary habit and Helicobacter pylori infection in early gastric cancer patient. Cancer Res Treat. 2002; 34:104–110.
30. Kim HJ, Chang WK, Kim MK, Lee SS, Choi BY. Dietary factors and gastric cancer in Korea: a case-control study. Int J Cancer. 2002; 97:531–535. PMID: 11802218.
Article
31. Lee JK, Park BJ, Yoo KY, Ahn YO. Dietary factors and stomach cancer: a case-control study in Korea. Int J Epidemiol. 1995; 24:33–41. PMID: 7797354.
Article
32. Kono S, Hirohata T. Nutrition and stomach cancer. Cancer Causes Control. 1996; 7:41–55. PMID: 8850434.
Article
33. Kim HJ, Lim SY, Lee JS, Park S, Shin A, Choi BY, et al. Fresh and pickled vegetable consumption and gastric cancer in Japanese and Korean populations: a meta-analysis of observational studies. Cancer Sci. 2010; 101:508–516. PMID: 19860848.
Article
34. Messina MJ, Persky V, Setchell KD, Barnes S. Soy intake and cancer risk: a review of the in vitro and in vivo data. Nutr Cancer. 1994; 21:113–131. PMID: 8058523.
35. Kim J, Kang M, Lee JS, Inoue M, Sasazuki S, Tsugane S. Fermented and non-fermented soy food consumption and gastric cancer in Japanese and Korean populations: a meta-analysis of observational studies. Cancer Sci. 2011; 102:231–244. PMID: 21070479.
Article
36. Ko KP, Park SK, Park B, Yang JJ, Cho LY, Kang C, et al. Isofl avones from phytoestrogens and gastric cancer risk: a nested case-control study within the Korean Multicenter Cancer Cohort. Cancer Epidemiol Biomarkers Prev. 2010; 19:1292–1392. PMID: 20447921.
37. Goldman R, Shields PG. Food mutagens. J Nutr. 2003; 133(Suppl 3):965S–973S. PMID: 12612183.
Article
38. Sinha R, Rothman N. Exposure assessment of heterocyclic amines (HCAs) in epidemiologic studies. Mutat Res. 1997; 376:195–202. PMID: 9202756.
Article
39. Yoo KY. Cancer control activities in the Republic of Korea. Jpn J Clin Oncol. 2008; 38:327–333. PMID: 18407932.
Article
40. Kim Y, Jun JK, Choi KS, Lee HY, Park EC. Overview of the National Cancer screening programme and the cancer screening status in Korea. Asian Pac J Cancer Prev. 2011; 12:725–730. PMID: 21627372.
41. Choi KS, Jun JK, Lee HY, Park S, Jung KW, Han MA, et al. Performance of gastric cancer screening by endoscopy testing through the National Cancer Screening Program of Korea. Cancer Sci. 2011; 102:1559–1564. PMID: 21564421.
Article
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