Int J Stem Cells.  2013 Nov;6(2):87-91.

Biomimetic Polymer Scaffolds to Promote Stem Cell-Mediated Osteogenesis

• Ko E
• Cho SW

Abstract

Bone tissue engineering using stem cells with osteogenic potential is a promising avenue of research for bone defect reconstruction. Organic, inorganic, and composite scaffolds have all been engineered to provide biomimetic microenvironments for stem cells. These scaffolds are designed to promote stem cell osteogenesis. Here, we review current technologies for developing biomimetic, osteoinductive scaffolds for stem cell applications. We summarize the reported in vitro and in vivo osteogenic effects of these scaffolds on stem cells.

Keyword

Bone tissue engineering; Biomimetic scaffolds; Stem cells; Osteoinductivity

MeSH Terms

Biomimetics*
Bone and Bones
Osteogenesis*
Polymers*
Stem Cells
Polymers