Nucl Med Mol Imaging.
2015 Sep;49(3):170-173. 10.1007/s13139-015-0358-9.
Future Perspectives of Radionanomedicine Using the Novel Micelle-Encapsulation Method for Surface Modification
- Affiliations
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- 1Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. dsl@snu.ac.kr
- 2Department of MolecularMedicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea.
- 3Department of Nuclear Medicine, Seoul National University Hospital, 101, Daehak-ro, Jongno-gu Seoul 110-744, Republic of Korea.
- KMID: 2052050
- DOI: http://doi.org/10.1007/s13139-015-0358-9
Abstract
- The emerging radionanomedicine has multifunctional and theranostic purposes. For these purposes, radionanomedicine should achieve the efficient and specific delivery of therapeutic agents by multifunctional characteristics, using low amounts of nanomaterials in vivo. Recent research on radiolabeled micelle-encapsulated nanomaterials has been made on the their efficacy and safety using a one-step surface modification method (Jeong's method). This one-step multifunctional approach to the nanoparticle can be the important challenge in producing effective nanoplatforms for cancer imaging and therapy.
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