Tuberc Respir Dis.
2002 Feb;52(2):186-191. 10.4046/trd.2002.52.2.186.
A Case of Primary Pulmonary Sarcoma with Morphologic Features of Malignant Fibrous Histiocytoma
- Affiliations
-
- 1Department of Internal Medicine, Catholic University of Korea, School of Medicine, Seoul, Korea. cmcpsh@cmc.cuk.ac.kr
- 2Department of Clinical pathology, Catholic University of Korea, School of Medicine, Seoul, Korea.
- KMID: 2050268
- DOI: http://doi.org/10.4046/trd.2002.52.2.186
Abstract
- A malignant fibrous histiocytoma is a malignant soft tissue neoplasm that occurs frequently in the metaphyseal ends of the long bones of adults. The lung is a common site for metastasis but it is a rare site for a primary malignant fibrous histiocytoma. Here we report a case of a primary malignant fibrous histiocytoma of the lung. The patient was a 53-year-old man who presented with a moderate amount of a left pleural effusion and an ill-defined mass in the left lower lobe on a chest radiograph and a local invasion to the left 10th and 11th rib on chest CT. Under the strong suspicion of lung cancer with a pleural invasion, a serial diagnostic thoracentesis was performed. The cytologic examination of the pleural effusion revealed no malignant cells. Consequently, a thoracoscopic pleural biopsy was performed. The histological examination revealed slender spindle cells and scattered epitheloid cells arranged in a vague storiform or a whirling pattern. Immunohistochemically, the tumor cells tested positive for vimentin and negative for cytokeratin, desmin, CD34 and PAS. These features were consistent with a malignant fibrous histiocytoma. This case is an unusual addition to the small number of published reports on a primary malignant fibrous histiocytoma of the lung.
