Tuberc Respir Dis.  2013 May;74(5):222-225. 10.4046/trd.2013.74.5.222.

Primary Malignant Fibrous Histiocytoma of the Pleura

• Cho KH
• Park C
• Hwang KE
• Hwang YR
• Seol CH
• Choi KH
• Lee MK
• Choi SH
• Kim HR
• Jeong ET

• KMID: 2050890
• DOI: http://doi.org/10.4046/trd.2013.74.5.222

Abstract

Malignant fibrous histiocytoma, a type of sarcoma, is a malignant neoplasm with uncertain origin that arises in both the soft tissues and the bone. The occurrence of primary malignant fibrous histiocytoma of the pleura is extremely rare. We report a case of a 65-year-old Korean man who is being diagnosed with primary malignant fibrous histiocytoma of the pleura.

Keyword

Histiocytoma, Malignant Fibrous; Pleura; Surgery

MeSH Terms

Histiocytoma, Malignant Fibrous
Pleura
Sarcoma

Figure

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  Figure 1 Chest radiograph (A) and chest computed tomography (B) showed diffuse pleural thickening.

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  Figure 2 Histopathological examination of the biopsy specimen showed anaplastic cytomorphology, with marked nuclear pleomorphism and atypical mitoses (A, H&E stain, ×100). These tumor cells stained positively for vimentin (B, ×400) and CD68 (C, ×400).

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  Figure 3 Positron emission tomography-computed tomography showed multinodular hypermetabolic lesion (standardized uptake value, 13.2) at the posterior pleural aspect, with mediastinal lymph node metastasis in the upper right and lower paratracheal nodes.

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