Clin Pediatr Hematol Oncol.  2010 Apr;17(1):64-68.

A Case of Idiopathic Hypereosinophilic Syndrome Presenting with Skin Manifestation in a Child

• La KS
• Nam HK
• Han JJ
• Woo CW
• Lee JH
• Lee KC

Abstract

Hypereosinophilic syndrome (HES) represents a heterogeneous group of diseases which is very rare in children. The authors experienced IHES (Idiopathic HES) in a 22-month-old child who presented with skin manifestations. He first visited out-patient clinic due to skin pustules and rash on palms and soles. His general condition was good except for itching sense on skin manifestations. On the lab finding, total eosinophil count was elevated and other labs showed nonspecific findings including parasite, allergy and immunology studies. We have taken the biopsy on the skin manifestations and it was consistent with IHES. He treated with oral steroid and the skin manifestations disappeared. We report a case of IHES with skin manifestations which clinically well responded to oral steroid without improvement of hematologic findings.

Keyword

Idiopathic hypereosinophilic syndrome; Skin manifestations; Child

MeSH Terms

Biopsy
Child
Eosinophils
Exanthema
Humans
Hypereosinophilic Syndrome
Infant
Outpatients
Parasites
Pruritus
Pyridines
Skin
Skin Manifestations
Thiazoles
Pyridines
Thiazoles