Brain Tumor Res Treat.  2013 Oct;1(2):107-110. 10.14791/btrt.2013.1.2.107.

Fulminant Meningitis after Radiotherapy for Clival Chordoma

Affiliations
  • 1Department of Neurosurgery, Eulji University Hospital, College of Medicine, Eulji University, Daejeon, Korea. nsksm@eulji.ac.kr

Abstract

The best treatment for clival chordoma is obtained with total surgical excision, sometimes combined with adjuvant radiotherapy. A cerebrospinal fluid (CSF) fistula is a fatal complication that may occur following extended transsphenoidal surgery (TSS) and adjuvant radiotherapy. We report a case of fulminant meningitis without a CSF fistula in a 57-year-old woman who underwent TSS and multiple radiotherapies for a clival chordoma. She presented to our emergency room with copious epistaxis and odor inside her nasal cavity and had an unexpected fatal outcome. She was diagnosed with meningitis based on CSF culture and blood culture. While treating clival chordomas with adjuvant radiotherapy, clinicians should be aware of the possibility of fulminant meningitis.

Keyword

Chordoma; Radiotherapy; Meningitis

MeSH Terms

Cerebrospinal Fluid
Chordoma*
Emergencies
Epistaxis
Fatal Outcome
Female
Fistula
Humans
Meningitis*
Middle Aged
Nasal Cavity
Odors
Radiotherapy*
Radiotherapy, Adjuvant
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