J Cardiovasc Ultrasound.  2014 Sep;22(3):160-161. 10.4250/jcu.2014.22.3.160.

Unusual Cardiac Infiltration in Diffuse Large B-Cell Lymphoma

• Moustafa S
• Patton DJ
• Alvarez N
• Prieur T
• Connelly M
• Alnasser M
• Mookadam F

• KMID: 2045436
• DOI: http://doi.org/10.4250/jcu.2014.22.3.160

Abstract

No abstract available.

Keyword

Diffuse B-cell lymphoma; Cardiac involvement; Echocardiography; Computed tomography; Magnetic resonance

MeSH Terms

Echocardiography
Lymphoma, B-Cell*

Figure

• 

  Fig. 1 Contrast-enhanced computed tomography showing a large heterogeneous anterior mediastinal mass (arrows) invading the mediastinal structures and left anterior chest wall with encirclement and compression of the main and left pulmonary arteries (A). The mass invaded the pericardium and was inseparable from the ventricular walls (B and C). Transthoracic echocardiogram parasternal short axis view showing a large mass encircling the anterior and lateral left ventricular walls (arrows) (D). LPA: left pulmonary artery, MPA: main pulmonary artery, RPA: right pulmonary artery, LV: left ventricle.

• 

  Fig. 2 A: Axial T1-weighted imaging showing the mass inseparable from the left ventricular wall (arrows). B: Short-axis T2-weighted imaging showing myocardial edema in the anterior and lateral walls of the left ventricle (arrowheads) with high signal intensity of the mass (arrow). C: Short-axis late gadolinium enhancement imaging showing non-ischemic sub-epicardial to mid wall late enhancement involving the anterior wall with extension to a small portion of anterior septum/anterolateral walls (arrows). LA: left atrium, LV: left ventricle, RA: right atrium, RV: right ventricle.

Reference

1. Savage KJ. Primary mediastinal large B-cell lymphoma. Oncologist. 2006; 11:488–495.

2. O'Mahony D, Peikarz RL, Bandettini WP, Arai AE, Wilson WH, Bates SE. Cardiac involvement with lymphoma: a review of the literature. Clin Lymphoma Myeloma. 2008; 8:249–252.

3. Yang CC, Tsai HW, Lai ST, Wu HC, Lo CY, Chang Y. Mediastinal diffuse large B-cell lymphoma invading the left atrium mimicking coronary artery disease with a mural thrombus. J Chin Med Assoc. 2012; 75:606–609.

4. Goldman M, Matthews R, Meng H, Bilfinger T, Kort S. Evaluation of cardiac involvement with mediastinal lymphoma: the role of innovative integrated cardiovascular imaging. Echocardiography. 2012; 29:E189–E192.

5. Bley TA, Zeiser R, Ghanem NA, Hackanson B, Brink I, Langer M. High grade cardiac lymphoma vitality monitoring by gadolinium-enhanced magnetic resonance imaging (MRI). In Vivo. 2005; 19:689–693.