Korean J Dermatol.  2007 May;45(5):458-461.

A Case of Secondary Cutaneous Diffuse Large B-cell Lymphoma

• Seung NR
• Jung SJ
• Park EJ
• Kim CW
• Cho HJ
• Kim KH
• Kim KJ

Abstract

Cutaneous, diffuse, large B-cell lymphoma (DLBCL) is characterized by a diffuse dermal infiltration which is composed of large centroblasts and immunoblasts. It is subdivided into a primary form arising from the skin and a secondary form which is metastasized from the lymph node. Secondary DLBCL has a more aggressive clinical course than the primary form. We report a 39-year-old female patient who presented with a 2 cm sized, erythematous, subcutaneous nodule on her left upper arm. She had been treated for brain-diffuse, large B-cell lymphoma which occurred 5 years before. The histopathologic and immunohistochemical examinations of the skin lesion also showed diffuse, large, B-cell lymphoma.

Keyword

Secondary cutaneous diffuse large B-cell lymphoma

MeSH Terms

Adult
Arm
B-Lymphocytes*
Female
Humans
Lymph Nodes
Lymphoma, B-Cell*
Skin