J Lab Med Qual Assur.  2008 Dec;30(2):267-271.

Evaluation of Dimension Hemoglobin A1c as an Emergency Outpatient Test

• Park MJ
• Shin MK
• Song W

Abstract

BACKGROUND
Hemoglobin A1c (HbA1c) is widely used for the diagnosis of diabetes and monitoring of glycemic control. Recently, there is an increasing demands of HbA1c as an emergency outpatient test. We performed this study to evaluate the clinical utility of Dimension HbA1c immunoassay (Dade Behring, Newark, DE, USA).
METHODS
Dimension HbA1c was evaluated for linearity, precision, method comparison, and speed. It was compared with VARIANT II Turbo (Bio-Rad Laboratories, Hercules, CA, USA).
RESULTS
Dimension HbA1c showed within-run and total imprecision (CVs) of less than 2.0% and 2.5%, respectively. It revealed a good linearity to about 20%. Comparison studies between Dimension HbA1c and VARIANT II Turbo yielded a good correlation (r=0.990). The elapsed time for analysis was 7.5 min for the first specimen and 0.5 min for the succeeding ones.
CONCLUSIONS
Dimension HbA1c provides acceptable performances and is suitable for the the emergency outpatient test.

Keyword

Hemoglobin A1c (HbA1c); Dimension RXL; Immunoassay; Emergency test

MeSH Terms

Emergencies
Hemoglobins
Humans
Immunoassay
Outpatients
Hemoglobins