Korean J Hematol.  2004 Dec;39(4):223-227.

Comparison between Diagnostic Criteria for Disseminated Intravascular Coagulation (DIC) of the International Society on Thrombosis and Hemostasis (ISTH) and the Korean Society on Thrombosis and Hemostasis (KSTH)

• Han KC
• Kim SH
• Lee SJ
• Kim DH
• Ko EH
• Jang MJ
• Chong SY
• Lee JS
• Oh D

Abstract

BACKGROUND
The criteria set by the International Society on Thrombosis and Hemostasis (ISTH) with the criteria of the Korean Society on Thrombosis and Hemostasis (KSTH) for the diagnosis of DIC was compared to evaluate the agreement between two criteria and the characteristics of each criteria.
METHODS
Two hundred ninety-six adult patients with sepsis (57 pneumonia, 75 hepatobiliary and gastrointestinal infection, 25 urinary tract infection, 51 infection associated with malignant diseases and 84 other causes) were studied. The rate of agreement in the diagnosis of DIC by the two diagnostic systems was analyzed. Characteristics of each criteria was also analyzed by the comparison of laboratory criteria.
RESULTS
The kappa coefficient and concordance rate, agreement parameters in the diagnosis of DIC by the two diagnostic systems was 0.78 and 89.5%, respectively. The median platelet count was lower and FDP level was higher in the patients diagnosed by ISTH criteria than in patients diagnosed by KSTH criteria.
CONCLUSION
The agreement between ISTH and KSTH criteria was significantly high.

Keyword

DIC; ISTH; KSTH; Diagnostic criteria

MeSH Terms

Adult
Dacarbazine
Diagnosis
Disseminated Intravascular Coagulation*
Hemostasis*
Humans
Platelet Count
Pneumonia
Sepsis
Thrombosis*
Urinary Tract Infections
Dacarbazine