Korean J Obstet Gynecol.  2010 Dec;53(12):1129-1135. 10.5468/kjog.2010.53.12.1129.

Sclerosing stromal tumors of the ovary occurred in various ages

• Kim JY
• Cha SH
• Jin SY
• Kim MK
• Choi GY
• Lee JJ
• Lee IS

• KMID: 2037515
• DOI: http://doi.org/10.5468/kjog.2010.53.12.1129

Abstract

Sclerosing stromal tumor (SST) of the ovary is a rare, benign tumor. The most common clinical symptom is menstrual irregularity. Diagnosis of SST is often made by postoperative pathologic examination. The important differential diagnoses are other sex cord stromal tumors including fibroma, thecoma and etc. We present four cases of SST of the ovary during 10 years with a brief review of the literature.

Keyword

Sclerosing stromal tumor; Ovary; Sex cord stromal tumor

MeSH Terms

Diagnosis, Differential
Female
Fibroma
Ovary
Sex Cord-Gonadal Stromal Tumors
Thecoma

Figure

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  Fig. 1 (A) Abdomen X-ray shows a 3.6×2.4 cm calcified mass. (B) Contrast-enhanced computed tomography scans shows a 12.6×7.4×13.3 cm mass with peripheral enhancement.

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  Fig. 2 (A) Magnetic resonance imaging on dynamic contrast enhanced image, the tumor reveal early peripheral enhancement with centripetal progression. (B) T2-weighted image shows low-intensity nodules set against high-intensity stroma.

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  Fig. 3 This photograph is cut surface of the both ovarian masses of case 1. (A) The right ovary, measuring 13.5 cm in diameter, is totally replaced by whitish gray solid firm mass. (B) The wedge resected left ovary shows a cystic follicle in the upper portion and a 0.5 cm sized whitish firm mass in the lower portion.

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  Fig. 4 This photograph is microscopic findings. (A) The right tumor of case 1 is composed of spindle cells and polyhedral cells with numerous vasculature (H&E stain, ×200). (B) The left tumor of case 1 consists of fibrotic stroma and occasional calcification (upper) alternating with the cellular area (H&E stain, ×100). (C) Immunohistochemistry of case 1 exhibit positive staining for smooth muscle actin in the perivascular polygonal cells (Avidin biotin complex for actin, ×200). (D) Low power view of case 3 demonstrates typical pseudolobular pattern of cellular area and loose edematous stromal portion (H&E stain, ×40).

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  Fig. 5 Ultrasonography shows a 7.1×5.9 cm sized, mixed echogenic mass with multiple focal hypoechoic area.

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