Prognostic parameters in Renal Cell Carcinoma

Kim, Dong Sun; Koh, Sung Kun

Abstract

This Study was designed to characterize the unfavorable prognostic factors of renal cell carcinoma through reviewing 27 cases with radical nephrectomy during the past 10 years from 1976 through 1986. The presence or absence of tumor invasion into renal capsule, perinephric fat, renal vein, regional lymph node, pelvis and/or ureter, hematuria at the time of first examination and the difference in the size of tumor and tumor cell type were studied. The 100 person-year mortality rates were analyzed with the chosen prognostic variables. Tests of significance between the difference in mortality rates of each two groups with or without a given characteristics were performed with Z-test. Author results as follows. : 1. The survival rate was decreased independently by the unfavorable factors such as the presence of tumor invasion into renal vein, regional lymph node, pelvis and/or ureter and tumor cell type other than clear cell(P<0.001, <0.001, <0.001, <0.05 respectively). 2. The survival rate was not affected by the following factors such as the presence or absence of hematuria at the time of first examination, tumor invasion into renal capsule, perinephric fat and the difference in size of tumor.