J Korean Soc Clin Toxicol.
2014 Jun;12(1):31-34.
A Case of Acute Hepatic Failure due to Acetaminophen Overdose Treated with Molecular Adsorbents Recirculating System(R)
- Affiliations
-
- 1Department of Emergency Medicine, Yonsei University College of Medicine, Seoul, Korea. emstar@yuhs.ac
Abstract
- We report on a patient who developed acute hepatic failure despite intravenous N-acetyl cysteine therapy who was treated with the Molecular Adsorbents Recirculating System (MARS). She presented 20 hours after the ingestion of 13 g of acetaminophen. The MARS is based on albumin dialysis principle which can be applied for patients with acute poisoning from drugs that have high protein-binding capacity because of its ability to selectively remove from circulation protein-bound toxins. The clinical toxicologist should be consider this technology when treating patients with hepatic failure following acetaminophen poisoning.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Use of the Molecular Adsorbent Recirculating System in Acute Fatty Liver of Pregnancy: a Case Report
- Acetaminophen Poisoning
- Acetaminophen-Induced Acute Liver Failure
- Effect of 4-Methylpyrazole for Acetaminophen Hepatotoxicity in a Rat Model
- The Clinical Use of the Plasma Acetaminophen Halflife in NAC-treated Acetaminophen Overdose
