Korean J Obstet Gynecol.  2003 Jan;46(1):184-187.

A case of McCune-Albright syndrome

Affiliations
  • 1Department of Obstetrics and Gynecology, College of Medicine, Catholic University, Seoul, Korea.

Abstract

McCune-Albright syndrome is a rare disease. It's triad is 1) precocious puberty, 2) fibrous dysplasia of bone and 3) caf-al-lait spots on skin. The cause is known as the mutation of subunit of G protein. Although there are some suggestions of treatment regimens including antiestrogen and GnRH agonist, at present, the accurate management is not known. We have experienced a case of McCune-Albright syndrome who has precocious puberty and fibrous dysplasia without caf-al-lait spot, and we present the case with a review of related literatures.

Keyword

McCune-Albright syndrome; precocious puberty; fibrous dysplasia; caf-al-lait spots; G-protein

MeSH Terms

Estrogen Receptor Modulators
Fibrous Dysplasia of Bone
Fibrous Dysplasia, Polyostotic*
Gonadotropin-Releasing Hormone
GTP-Binding Proteins
Puberty, Precocious
Rare Diseases
Skin
Estrogen Receptor Modulators
GTP-Binding Proteins
Gonadotropin-Releasing Hormone
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