J Korean Neurol Assoc.
1991 Jun;9(2):220-227.
The Effect of Zonisamide in Epileptic Patients
- Affiliations
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- 1Department of Neurology, Catholic University, Korea.
- 2Medical Institute, Bucheon Jeil Hospital, Korea.
Abstract
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We have studied thirty two cases of inappropriately treatable and intractable epileptics to various anti-convulsants. Zonisamide had a definite anti-epileptic activity in eleven subjects(52.4%) of intractble epilepsy. Five patients(45.5%), who were previously inappropriately treatable epileptic patients became seizure free on zonisamide. Two subjects were withdrawn from study because of side effect and two subjects were also withdrawn because of uncontrolled seizure. Zonisamide is not only effective in intractable epileptic patients but also in first trial for untreated epileptic patients.