Korean J Dermatol.  2007 Jan;45(1):76-78.

High Dose UVA-1 Phototherapy for Morphea

Affiliations
  • 1Department of Dermatology, Kosin University College of Medicine, Busan, Korea. ksderm98@unitel.co.kr

Abstract

Morphea is a rare, sclerotic connective tissue disorder and is thought to be caused by a decreased collagenase activity. Numerous treatment modalities have been tried, such as infiltration with glucocorticosteroid, D-penicillamine, antimalarial agents and cyclosporine. However, all have shown only limited success. We report a case of a 21 year- old female with localized scleroderma, who showed a marked improvement after localized therapy with high dose UVA-1.

Keyword

Collagenase I; High dose UVA-1; Morphea

MeSH Terms

Antimalarials
Collagenases
Connective Tissue
Cyclosporine
Female
Humans
Penicillamine
Phototherapy*
Scleroderma, Localized*
Antimalarials
Collagenases
Cyclosporine
Penicillamine
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