Korean J Dermatol.  2002 May;40(5):540-544.

Primary Systemic Ki-1(CD30)-positive Large Cell Lymphoma

• Woo MJ
• Lee SW
• Chung H
• Kim SW
• Yoon GS

Abstract

We report a case of Ki-1(CD30) positive large cell lymphoma which developed on the skin of the right inguinal area in an 8-year-old boy. The lesion was a 3.0x5.0cm sized ulcerative tumor with elevated margin, rapidly growing during 2 week period and was associated with enlargement of the left inguinal lymph nodes. Histopathologic feature showed anaplastic large cells with abundant cytoplasm and multinucleated giant cells with wreath-like nuclei in the dermis and subcutis. Immunohistochemically, tumor cells were CD30 positive. He was treated with chemotherapy through BFM-NHL protocol, with good response.

Keyword

Ki-1(CD30) positive large cell lymphoma; 8-year old boy

MeSH Terms

Child
Cytoplasm
Dermis
Drug Therapy
Giant Cells
Humans
Lymph Nodes
Lymphoma*
Male
Skin
Ulcer