Korean J Dermatol.
2008 Mar;46(3):414-417.
A Case of CD30 (+)/ALK (-) Systemic Anaplastic Large Cell Lymphoma
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- 1Department of Dermatology, School of Medicine, Keimyung University, Daegu, Korea. franzes@dsmc.or.kr
Abstract
- Systemic CD30 positive anaplastic large cell lymphoma (ALCL), a subtype of non-Hodgkin lymphoma (NHL), developes in the internal organs and invades the skin. There have been many cases of primary cutaneous CD30 positive T-cell lymphoproliferative disorder, but reports of systemic ALCL have been rare. We describe herein CD30 positive ALK negative systemic ALCL in a 90-year-old woman with multiple masses and nodules on the skin, lung and liver, as well as enlargement of the hilar and abdominal lymph nodes, of 3 months duration. She died of sudden aggravation of the general condition after 7 days.
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