Korean J Cytopathol.  1998 Dec;9(2):233.

Fine Needle Aspiration Cytology of Clear Cell Sarcoma: A Case Report

• Lim SC
• Chung YK
• Kim DC
• Lee YK
• Shin ET

Abstract

Clear cell sarcoma(CCS) is an uncommon soft tissue sarcoma that occurs in tendons and aponeuroses, usually of the lower extremities and is believed to be of neural crest origin that have a capability to produce melanin. These tumors commonly metastasize and have a very poor prognosis. The fine needle aspiration cytologic finding of CCS is not well documented. We recently experienced a case of CCS. The patient was a 54-year-old male with painful swelling of the right inguinal area. Fine needle aspiration cytology revealed polygonal or fusiform tumor cells with clear or granular cytoplasm and vesicular nuclei containing one or two nucleoli. Im munohistochemical staining for S-100 protein and HMB-45 revealed strong positivity, and variable developing stages of premelanosomes were observed by electron microscopy in the excised specimen.

Keyword

Clear cell sarcoma; Fine needle aspiration cytology

MeSH Terms

Biopsy, Fine-Needle*
Cytoplasm
Humans
Lower Extremity
Male
Melanins
Microscopy, Electron
Middle Aged
Neural Crest
Prognosis
S100 Proteins
Sarcoma
Sarcoma, Clear Cell*
Tendons
Melanins
S100 Proteins