Korean J Obstet Gynecol.  2011 Apr;54(4):218-222. 10.5468/KJOG.2011.54.4.218.

Ovarian dysgerminoma associated with pregnancy

• Lee YK
• Yoo CY
• Lee G
• Park DC

• KMID: 2013245
• DOI: http://doi.org/10.5468/KJOG.2011.54.4.218

Abstract

A case of a 33-year-old 3 gravida, 1 para pregnant woman in the 7th week of gestation who was concurrented with dysgerminoma is presented. Measurements were made on serum lactic dehydrogenase, alpha-fetoprotein, CA-125, and pelvicmagnetic resonance imaging. The clinical stage was IA and right salpingo-oophorectomy and biopsy of the left ovary were done preserving the pregnancy. A cytological finding was non-specific. The frequency of malignant ovarian tumors associated with pregnancy and the treatment for it were discussed.

Keyword

Dysgerminoma of ovary; Pregnancy

MeSH Terms

Adult
alpha-Fetoproteins
Biopsy
Dysgerminoma
Female
Humans
Ovary
Oxidoreductases
Pregnancy
Pregnant Women
Oxidoreductases
alpha-Fetoproteins

Figure

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  Fig. 1 Ultrasonographic findings. (A). Fetal heart rate is normal (B). The mass had multilocular profiles with some solid parts, and its wall looked slightly thick (C). The vascularization of tumor mass was checked and the resistance index (RI) was calculated. RI=0.33 (D).

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  Fig. 2 Pelvic magnetic resonance imaging without enhance was perfomed. It measured a 5.8×9.8 cm in sized and was a lobulating contoured mass with intermediate signal intensity in T2 images. And a 4.3×3.3 cm sized cystic lesion was also observed. (A) Sagittal view. (B) Axial view. Arrows: dysgerminoma.

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  Fig. 3 Laparoscopic finding. Laparoscopic right adnexectomy and contralateral ovary biopsy were performed.

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  Fig. 4 Microscopically, monotonous polygonal cells form well defined nests separated by fibrous stroma (A: H&E, ×100). In certain area tumors cells form cords or trabecular patterns (B: H&E, ×400).

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