J Korean Surg Soc.  2003 Dec;65(6):582-584.

Synchronous Double Primary Carcinoma of the Intrahepatic Bile Duct and the Gallbladder

• Choi YH
• Kim WY
• Lee KM
• Joo MJ

Abstract

A 66-year-old male was admitted to the department of surgery, at the Presbyterian Medical Center due to right upper quadrant pain. Tumor marker studies reported CEA and CA19-9 elevation. Liver function test was normal. Ultrasonography and computed tomography showed a single infiltrative tumor in the left lobe of liver, multiple lymphadenopathies around the common hepatic duct and intrahepatic bile duct dilatation of the left lobe. The gallbladder was nonspecific. During laparotomy, we found an ill-marginated and infiltrative tumor in the left lobe of liver, multiple enlarged lymph nodes around the common hepatic duct and cystic duct, and mild thickening of the gallbladder fundus wall. Left hepatic lobectomy and cholecystectomy were performed. Pathologic findings revealed that the liver tumor was a moderated differentiated adenocarcinoma with extension to the pericystic and pericommon hepatic lymph nodes and focal adenocarcinoma in situ of gallbladder mucosal wall with clear cystic duct resection margin. We therefore report a rare case of synchronous double primary cancer of the intrahepatic bile duct and gallbladder.

Keyword

Synchronous double primary cancer; Intrahepatic bile duct; Gallbladder

MeSH Terms

Adenocarcinoma
Aged
Bile Ducts, Intrahepatic*
Cholecystectomy
Cystic Duct
Dilatation
Gallbladder*
Hepatic Duct, Common
Humans
Laparotomy
Liver
Liver Function Tests
Lymph Nodes
Male
Protestantism
Ultrasonography