Korean J Vet Res.
2011 Mar;51(1):61-64.
Eosinophilic granulomas in two dogs
- Affiliations
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- 1College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690-756, Korea. kimjhoon@jejunu.ac.kr
- 2Gangnam Animal Medical Center, Busan 612-010, Korea.
- 3Cats and Dogs Animal Clinic, Seoul 121-250, Korea.
- 4College of Life Science and Natural Resources, Sangji University, Wonju 220-702, Korea.
- 5Department of Clinical Laboratory Science, Semyung University, Jecheon 390-711, Korea.
Abstract
- Eosinophilic granuloma is a common hypersensitive inflammatory skin disease in cats, and rare in dogs and horses. The skin biopsies of 5 years old female Cocker spaniel and 2 years old female mixed dog had the clinical signs of skin nodules with alopecia were submitted for diagnosis. Solitary skin nodules and papillary nodules were presented on the left external ear and back of Cocker spaniel and on the external ear of mixed dog, respectively. Histopathologically, epidermis of skin showed mild to severe hyperplasia with multifocal ulceration. Small to large irregular, brightly eosinophilic foci with degenerating eosinophils and homogeneous degenerated collagens were existed in the dermis of both ear and back skin. Typical 'flame figures', a mixture of degenerated collagen and degranulated eosinophils, were observed in both cases. Based on the histopathologic findings and special staining characters, 2 cases were diagnosed as canine eosinophilic granuloma. This is the first report for the eosinophilic granuloma of dogs in Korea.
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